Abstract The insertion of Pharmaceutical Care in Primary Health Care (PHC) improves patients’ clinical outcomes and quality of life. Pharmacotherapeutic follow-up can contribute to the management of chronic diseases such as diabetes, promoting better glycemic control and adherence to therapy. This study aimed to assess the Drug-therapy Problems (DTPs) and Pharmacist Interventions (PIs) on the pharmacotherapeutic management in patients with type 2 diabetes mellitus (T2DM) in a community pharmacy. A quantitative, retrospective, and cross-sectional study was conducted in a Pharmaceutical Care Program within the PHC in Juiz de Fora (Minas Gerais, Brazil). Inclusion criteria were patients with T2DM above 18, who attended at least three pharmaceutical consultations between July 2016 and October 2018 and presented two or more glycated hemoglobin tests. The study group (n = 17) was largely composed of women (65%), elderly (76%), sedentary (72%), and obese people (52%). The resolution was achieved in 79% of the DTPs identified (n = 115). Most of DTPs were related to administration and adherence to pharmacotherapy (46%). 60% of the 437 PIs involved the provision of information and counseling. In other words, accessible interventions lead to high resolvability. Therefore, clinical actuation of pharmacists could improve the prognosis in diabetes treatment.

Resumo Objetivos Identificar os fatores associados à não adesão à farmacoterapia em pessoas idosas brasileiras no âmbito da atenção primária à saúde (APS) através da realização de uma revisão sistemática da literatura. Método Trata-se de uma revisão sistemática da literatura nos idiomas inglês, espanhol e português, realizada na biblioteca eletrônica SciELO e nas bases de dados eletrônicas MEDLINE - via PubMed, LILACS, Embase e Web of Science no período de janeiro de 2010 a junho de 2020. A seleção dos estudos foi realizada de maneira independente por dois revisores, por meio do aplicativo de seleção Rayyan. Resultados Após a aplicação dos critérios de elegibilidade, foram incluídos nove estudos na revisão sistemática. O principal método utilizado para mensurar o desfecho foi a Escala de Morisky-Green (4-itens). Os resultados apontam as dificuldades de acesso aos medicamentos, as multimorbidades, a polifarmácia, o uso de medicamentos potencialmente inapropriados para idosos, o grau de confiança no profissional médico, as crenças, a autopercepção de saúde negativa e a incapacidade funcional como os principais fatores associados à não adesão à farmacoterapia na APS. Conclusões No âmbito da APS, a não adesão à farmacoterapia pela população idosa se apresenta como um problema muito frequente, sendo desencadeado por múltiplos fatores e com consequências negativas para o controle das condições de saúde, para o uso racional de medicamentos e para um envelhecimento saudável. Destaca-se ainda que parte dos fatores associados são passíveis de intervenção nesse nível de atenção à saúde.

Abstract Objectives To identify the factors associated with non-adherence to pharmacotherapy in elderly Brazilians assisted by Primary Health Care (PHC) through a systematic review of the literature. Method This is a systematic literature review in English, Spanish, and Portuguese, performed in the SciELO electronic library and in the electronic databases MEDLINE - via PubMed, LILACS, Embase, and Web of Science from January 2010 to June 2020. Study selection was performed independently by two reviewers using the Rayyan selection application. Results After applying the eligibility criteria, nine studies were included in the systematic review. The most frequent method used to measure the outcome was the Morisky-Green Scale (4-items). The results point that the main factors related to non-adherence to pharmacotherapy in PHC are difficulties in medication access, multimorbidities, polypharmacy, the use of potentially inappropriate medications for the elderly, the degree of trust in the medical professional, beliefs, negative self-perception of health and functional disability. Conclusions In the context of PHC, non-adherence to pharmacotherapy by the elderly population presents itself as a very frequent problem, being triggered by multiple factors and with negative consequences for the control of health conditions, the rational use of medications, and healthy aging. It is also noteworthy that part of the associated factors are subject to intervention at this level of health care.

Resumo Objetivos Verificar a prevalência do sofrimento psíquico em uma população de idosos da comunidade e analisar a sua correlação com idade, anos de escolaridade, nível socioeconômico, sexo, morbidade referida, autopercepção de saúde, autopercepção visual, autopercepção auditiva e síndromes geriátricas (fragilidade, medo de cair, capacidade funcional e quedas). Método Estudo transversal com 315 idosos, não institucionalizados, residentes em Juiz de Fora, Minas Gerais, Brasil, em 2015. Os dados foram coletados através de inquérito domiciliar e o sofrimento psíquico pode ser observado naquela população idosa com a aplicação do Patient Health Questionnaire (PHQ-4). Para verificar a associação da variável desfecho com as variáveis explicativas, usou-se teste qui-quadrado (χ²) de Pearson. O nível de significância adotado no estudo foi de 5%. Resultados A prevalência de sofrimento psíquico entre os idosos foi de 41,8% (IC95% 36,5–47,4%). Verificou-se associação entre o PHQ-4 e sexo (ρ=0,001), morbidade referida (ρ=0,020), autopercepção de saúde (ρ<0,001), autopercepção visual (ρ=0,001), autopercepção auditiva (ρ=0,034), capacidade funcional (ρ=0,003) e fragilidade (ρ=0,000) Conclusões o sofrimento psíquico é uma condição frequente entre idosos. O conhecimento dos fatores associados a esse evento pode contribuir para um modelo de cuidado em saúde que estimule o envelhecimento ativo e saudável.

Abstract Objectives To verify the prevalence of psychic suffering in an old population in the community and analyze its correlation with age, years of education, socioeconomic level, gender, reported morbidity, self-perceived health, visual self-perception, self-perception of hearing, and geriatric syndromes (frailty, fear of falling, functional capacity, and falls). Method A cross-sectional study with 315 non-institutionalized old people living in Juiz de Fora, Minas Gerais, Brazil, in 2015. Data were collected through a household survey, and the psychic suffering can be observed in that old population with the use of the Patient Health Questionnaire (PHQ-4). The Pearson’s chi-square test (χ²) was used to verify the association between the outcome variable and the explanatory variables. The level of significance adopted in the study was 5%. Results The prevalence of psychic suffering among the old people was 41.8% (95% CI 36.5–47.4%). There was an association between the PHQ-4 and gender (ρ=0.001), reported morbidity (ρ=0.020), self-perceived health (ρ <0.001), visual self-perception (ρ=0.001), self-perception of hearing (ρ=0.034), functional capacity (ρ=0.003), and fragility (ρ=0.000). Conclusions psychic suffering is a common condition among old people. Knowledge of the factors associated with this event can contribute to a health care model that encourages active and healthy aging.